Hersteller |
Boster
|
Kategorie |
|
Typ |
Antibody |
Specific against |
Human, Mouse |
Format |
Liquid |
Applikationen |
WB |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
BOS-A03161 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
Amino Acid Metabolism, Amino Acids, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction |
Short Description |
Boster Bio Anti-GGH/Gamma Glutamyl Hydrolase Antibody (Catalog # A03161). Tested in WB applications. This antibody reacts with Human, Mouse. |
Description |
Boster Bio Anti-GGH/Gamma Glutamyl Hydrolase Antibody (Catalog # A03161). Tested in WB applications. This antibody reacts with Human, Mouse. |
Background |
Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
Yao R., Proc. Natl. Acad. Sci. U.S.A. 93:10134-10138(1996). Yin D., Gene 238:463-470(1999). Basrur V., J. Proteome Res. 2:69-79(2003). |
Gene Name |
GGH |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Contents |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application Details |
Western blotting: 1:500~1:3000 |
Immunogen |
Synthesized peptide derived from internal of human GGH. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Gamma-glutamyl hydrolase |
Molecular Weight |
35964 MW |
Protein Function |
Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha- glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. |
Subcellular Localization |
Secreted, extracellular space. Lysosome. Melanosome. While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.. |
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