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Anti-GGH/Gamma Glutamyl Hydrolase Antibody

Anti-GGH/Gamma Glutamyl Hydrolase Antibody

ArtNr	BOS-A03161
Hersteller	Boster
Menge	100 ul
Kategorie	Food Safety Vitamines Antibodies Western Blot Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Gamma-glutamyl hydrolase;3.4.19.9;Conjugase;GH;Gamma-Glu-X carboxypeptidase;GGH;
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	35964 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000
Manufacturer - Gene Name	GGH
Gene Full Name	Gamma-glutamyl hydrolase
Background	Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. Yao R., Proc. Natl. Acad. Sci. U.S.A. 93:10134-10138(1996). Yin D., Gene 238:463-470(1999). Basrur V., J. Proteome Res. 2:69-79(2003).
Immunogen	Synthesized peptide derived from internal of human GGH.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Amino Acid Metabolism, Amino Acids, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction
Protein Function	Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha- glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
Subcellular Localization	Secreted, extracellular space. Lysosome. Melanosome. While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Short Description	Boster Bio Anti-GGH/Gamma Glutamyl Hydrolase Antibody (Catalog # A03161). Tested in WB applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-GGH/Gamma Glutamyl Hydrolase Antibody (Catalog # A03161). Tested in WB applications. This antibody reacts with Human, Mouse.

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BOS-A03161-datasheet.pdf

BOS-A03161-safety-datasheet.pdf