Anti-P23 PTGES3 Antibody

Primary Antibodies

Serum

WB, 1:1, 000, colorimetric, Human, Mouse, Rat

Ski-like protein

Antiserum.

Cancer, Cancer Metabolism, Chaperones, Chromosome Structure, Endocrine Metabolism, Epigenetics and Nuclear Signaling, Heat Shock Proteins, Hormone Biosynthesis, Lipid Metabolism, Metabolic Signaling Pathway, Metabolism, Pathways and Processes, Protein Trafficking, Signal Transduction

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).