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Anti-LTK Antibody Europäischer Partner

ArtNr BOS-A04217
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Leukocyte tyrosine kinase receptor;2.7.10.1;Protein tyrosine kinase 1;LTK;TYK1;
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
91681 MW
Clonality
Polyclonal
Application Details
Western blotting: 1:500~1:3000
Manufacturer - Gene Name
LTK
Gene Full Name
Leukocyte tyrosine kinase receptor
Background
Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.
Toyoshima H., Proc. Natl. Acad. Sci. U.S.A. 90:5404-5408(1993).
Krolewski J.J., EMBO J. 10:2911-2919(1991).
Maru Y., Oncogene Res. 5:199-204(1990).
Immunogen
Synthesized peptide derived from internal of human LTK.
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
Energy Metabolism, Energy Transfer Pathways, Growth Factors/Hormones, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Protein Phosphorylation, Receptor Tyrosine Kinases, Signal Transduction, Tyrosine Kinases
Protein Function
Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.
Subcellular Localization
Membrane; Single-pass type I membrane protein.
Short Description
Boster Bio Anti-LTK Antibody (Catalog # A04217). Tested in WB applications. This antibody reacts with Human, Mouse.
Description
Boster Bio Anti-LTK Antibody (Catalog # A04217). Tested in WB applications. This antibody reacts with Human, Mouse.
Tissue Specificity
Expressed in non-hematopoietic cell lines and T- and B-cell lines.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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