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Anti-ARHGEF11/Pdz Rhogef Antibody

Anti-ARHGEF11/Pdz Rhogef Antibody

ArtNr	BOS-A04614
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Signaling Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Rho Subfamily
Typ	Antibody
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Rho guanine nucleotide exchange factor 11;PDZ-RhoGEF;ARHGEF11;KIAA0380;
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	167704 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000
Manufacturer - Gene Name	ARHGEF11
Gene Full Name	Rho guanine nucleotide exchange factor 11
Background	May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth. Nagase T., DNA Res. 4:141-150(1997). Gregory S.G., Nature 441:315-321(2006). Ruemenapp U., FEBS Lett. 459:313-318(1999).
Immunogen	Synthesized peptide derived from N-terminal of human ARHGEF11.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	G Protein Signaling, Ras Family, Regulators, Signal Transduction, Signaling Pathway, Small G Proteins
Protein Function	May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth.
Subcellular Localization	Cytoplasm. Membrane. Translocated to the membrane upon stimulation.
Short Description	Boster Bio Anti-ARHGEF11/Pdz Rhogef Antibody (Catalog # A04614). Tested in WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-ARHGEF11/Pdz Rhogef Antibody (Catalog # A04614). Tested in WB applications. This antibody reacts with Human.
Tissue Specificity	Ubiquitously expressed.

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BOS-A04614-datasheet.pdf

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