Hersteller |
Boster
|
Kategorie |
|
Typ |
Antibody |
Specific against |
Human, Mouse, Rat |
Format |
Liquid |
Applikationen |
WB, IHC |
Menge |
100ul |
Host |
Rabbit |
ArtNr |
BOS-A04972 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
Neural Signal Transduction, Neurology Process, Neuroscience |
Short Description |
Boster Bio Anti-Protein NDRG4 NDRG4 Antibody (Catalog # A04972). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat. |
Description |
Boster Bio Anti-Protein NDRG4 NDRG4 Antibody (Catalog # A04972). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat. |
Background |
Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress By similarity. May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.
Zhou R.-H., Genomics 73:86-97(2001). Nishimoto S., Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases. Qu X., Mol. Cell. Biochem. 229:35-44(2002). |
Gene Name |
NDRG4 |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Contents |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application Details |
Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100 |
Immunogen |
Synthesized peptide derived from internal of human NDRG4. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Protein NDRG4 |
Molecular Weight |
38459 MW |
Protein Function |
Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.. |
Subcellular Localization |
Cytoplasm, cytosol. |
Tissue Specificity |
Expressed predominantly in brain and heart (at protein level). In the brain, detected in astrocytes. Isoform 1 and isoform 2 are only expressed in brain. Isoform 3 is expressed in both heart and brain. Up-regulated in glioblastoma multiforme cells.. |
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