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Anti-Protein NDRG4 NDRG4 Antibody Europäischer Partner

ArtNr BOS-A04972
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Protein NDRG4;Brain development-related molecule 1;N-myc downstream-regulated gene 4 protein;Vascular smooth muscle cell-associated protein 8;SMAP-8;NDRG4;BDM1, KIAA1180;
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
38459 MW
Clonality
Polyclonal
Application Details
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Manufacturer - Gene Name
NDRG4
Gene Full Name
Protein NDRG4
Background
Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress By similarity. May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.
Zhou R.-H., Genomics 73:86-97(2001).
Nishimoto S., Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Qu X., Mol. Cell. Biochem. 229:35-44(2002).
Immunogen
Synthesized peptide derived from internal of human NDRG4.
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
Neural Signal Transduction, Neurology Process, Neuroscience
Protein Function
Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.
Subcellular Localization
Cytoplasm, cytosol.
Short Description
Boster Bio Anti-Protein NDRG4 NDRG4 Antibody (Catalog # A04972). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Description
Boster Bio Anti-Protein NDRG4 NDRG4 Antibody (Catalog # A04972). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Expressed predominantly in brain and heart (at protein level). In the brain, detected in astrocytes. Isoform 1 and isoform 2 are only expressed in brain. Isoform 3 is expressed in both heart and brain. Up-regulated in glioblastoma multiforme cells.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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