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Anti-IL11RA Antibody Europäischer Partner

ArtNr BOS-A06426
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Interleukin-11 receptor subunit alpha;IL-11 receptor subunit alpha;IL-11R subunit alpha;IL-11R-alpha;IL-11RA;IL11RA;
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
45222 MW
Clonality
Polyclonal
Application Details
Western blotting: 1:500~1:3000
Manufacturer - Gene Name
IL11RA
Gene Full Name
Interleukin-11 receptor subunit alpha
Background
Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
Cherel M., Blood 86:2534-2540(1995).
Van Leuven F., Genomics 31:65-70(1996).
Kalnine N., Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Immunogen
Synthesized peptide derived from C-terminal of human IL11RA.
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
Cancer, Cytokines, Hematopoietic Progenitors, Immunology, Innate Immunity, Interleukins, Receptors, Stem Cells, Surface Molecules, Tumor Biomarkers
Protein Function
Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
Subcellular Localization
Membrane; Single-pass type I membrane protein.
Short Description
Boster Bio Anti-IL11RA Antibody (Catalog # A06426). Tested in WB applications. This antibody reacts with Human.
Description
Boster Bio Anti-IL11RA Antibody (Catalog # A06426). Tested in WB applications. This antibody reacts with Human.
Tissue Specificity
Expressed in a number of cell lines, including the myelogenous leukemia cell line K-562, the megakaryocytic leukemia cell line M-07e, the erythroleukemia cell line TF-1, and the osteosarcoma cell lines, MG-63 and SaOS-2. Also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increased in prostate carcinoma.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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