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Anti-Diacylglycerol kinase eta DGKH Antibody Europäischer Partner

ArtNr BOS-A07077-1
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen IF, ICC, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias DGKH;Diacylglycerol kinase eta;DAG kinase eta;Diglyceride kinase eta;DGK-eta
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
134866 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry, 1:100 - 1:300
Immunofluorescence, 1:200 - 1:1000
ELISA, 1:20000
Not yet tested in other applications.
Manufacturer - Gene Name
DGKH
Gene Full Name
Diacylglycerol kinase eta
Immunogen
A peptide derived from human DGKH. Immunogen sequence location: 771-820
Contents
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction
Protein Function
Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.
Subcellular Localization
Cytoplasm. Cell membrane. Translocated from the cytoplasm to endosomes in response to stress stimuli (PubMed:12810723). Isoform 2 is rapidly relocated back to the cytoplasm upon removal of stress stimuli, whereas isoform 1 exhibits sustained endosomal association (PubMed:12810723). Translocates from the cytoplasm to the cell membrane in the presence of active GTP-bound form of HRAS (PubMed:19710016).
Short Description
Boster Bio Anti-Diacylglycerol kinase eta DGKH Antibody (Catalog# A07077-1). Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse.
Description
Boster Bio Anti-Diacylglycerol kinase eta DGKH Antibody (Catalog# A07077-1). Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse.
Tissue Specificity
Isoform 2 is ubiquitously expressed.Isoform 1 is expressed only in testis, kidney and colon.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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