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Anti-IRX3 Antibody Europäischer Partner

ArtNr BOS-A07258
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody
Format Liquid
Applikationen IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Iroquois-class homeodomain protein IRX-3;Homeodomain protein IRXB1;Iroquois homeobox protein 3;IRX3;IRXB1;
Lieferbar
Manufacturer - Category
Primary Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
52119 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry: 1:50~1:100
Manufacturer - Gene Name
IRX3
Gene Full Name
Iroquois-class homeodomain protein IRX-3
Background
Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells By similarity.
Hansen L., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Lewis M.T., Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
Immunogen
Synthesized peptide derived from internal of human IRX3.
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Manufacturer - Research Category
Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling, Neurogenesis, Neurology Process, Neuroscience, Oncoproteins, Oncoproteins/Suppressors, Transcription, Transcription Factors
Protein Function
Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells (By similarity).
Subcellular Localization
Nucleus.
Short Description
Boster Bio Anti-IRX3 Antibody (Catalog # A07258). Tested in IHC applications. This antibody reacts with Human, Mouse.
Description
Boster Bio Anti-IRX3 Antibody (Catalog # A07258). Tested in IHC applications. This antibody reacts with Human, Mouse.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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