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Anti-TMBIM1/Recs1 Antibody

Anti-TMBIM1/Recs1 Antibody

ArtNr	BOS-A10501
Hersteller	Boster
Menge	100 ug
Kategorie	Neuroscience Neuroinflammation Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Dry ice	Yes
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TMBIM1, Putative uncharacterized protein TMBIM1, Protein lifeguard 3, Protein RECS1 homolog, Transmembrane BAX inhibitor motif-containing protein 1, LFG3, RECS1, PP1201, PSEC0158
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Observed Molecular Weight	34607 MW
Manufacturer - Format	Liquid (sterile filtered)
Clonality	Polyclonal
Application notes	This protein A purified antibody has been tested for use in ELISA, Immunohistochemistry, and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 35 kDa in size corresponding to TMBIM-1 by western blotting in the appropriate cell lysate or extract. To date this antibody has shown the ability to recognize over-expressed TMBIM1 but not endogenous protein.
Application Details	ELISA: 1:10, 000 IHC: 10µg/mL WB: 1:500 - 1:2, 000
Manufacturer - Gene Name	TMBIM1
Gene Full Name	Protein lifeguard 3
Background	This antibody is suitable for Cancer, Immunology and Nuclear Signaling research. TMBIM1 (Transmembrane BAX inhibitor motif-containing protein 1) is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kB activation. A drosophila homolog of this protein (dNMDA1 with 40% homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.
Immunogen	This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the amino terminus of human TMBIM1 protein.
Contents	0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide
Purification	This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads. This antibody is specific for human TMBIM1 protein. A BLAST analysis was used to suggest partial cross-reactivity with TMBIM1 from mouse and rat sources based on ~88% homology with the immunizing sequence. Cross-reactivity with TMBIM1 from other sources has not been determined.
Concentration	1.2 mg/mL by UV absorbance at 280 nm
Manufacturer - Research Category	Cell Biology
Protein Function	Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
Subcellular Localization	Membrane; Multi-pass membrane protein. Lysosome membrane. Endosome membrane.
Short Description	Boster Bio Anti-TMBIM1/Recs1 Antibody (Catalog # A10501). Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-TMBIM1/Recs1 Antibody (Catalog # A10501). Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

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BOS-A10501-datasheet.pdf

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