Vergleich

Anti-RAD51L1 RAD51B Antibody

Hersteller Boster
Kategorie
Typ Antibody
Specific against Human, Mouse, Monkey
Isotype IgG
Format Liquid
Applikationen WB, IF, ELISA, IHC-P
Menge 100ul
Host Rabbit
ArtNr BOS-A20019
Targets RAD51B
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Manufacturers Product Category
Primary Antibodies
Manufacturers Research Category
DNA/RNA, DNA Damage & Repair, Epigenetics and Nuclear Signaling
Short Description
Boster Bio Anti-RAD51L1 RAD51B Antibody (Catalog# A20019). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Monkey.
Description
Boster Bio Anti-RAD51L1 RAD51B Antibody (Catalog# A20019). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Monkey.
Gene Name
RAD51B
Clonality
Polyclonal
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Application Details
Western Blot, 1:500 - 1:2000
Immunohistochemistry, 1:100 - 1:300
ELISA, 1:40000
Not yet tested in other applications.
Immunogen
A peptide derived from human RAD51L1. Immunogen sequence location: 201-250
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Storage
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name
DNA repair protein RAD51 homolog 2
Molecular Weight
42196 MW
Protein Function
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.
Subcellular Localization
Nucleus.
Tissue Specificity
Expressed in a wide range of tissues.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 02.05.2024 

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