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Anti-Vinculin VCL Antibody

Anti-Vinculin VCL Antibody

ArtNr	BOS-A30448
Hersteller	Boster
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB, IF, ICC, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	VCL;Vinculin;Metavinculin
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	123799 MW
Clonality	Polyclonal
Application Details	Western Blot, 1:500 - 1:2000 Immunohistochemistry, 1:100 - 1:300 Immunofluorescence, 1:200 - 1:1000 ELISA, 1:10000 Not yet tested in other applications.
Manufacturer - Gene Name	VCL
Gene Full Name	Vinculin
Immunogen	A peptide derived from human Vinculin. Immunogen sequence location: 786-835
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Actin Binding Proteins, Actin, etc., Cardiovascular, Contractility, Cytoskeleton, Cytoskeleton/ECM, Microfilaments, Signal Transduction
Protein Function	Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell- surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
Subcellular Localization	Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, focal adhesion.Cytoplasmic face of adhesion plaques. Recruitment to cell-cell junctions occurs in a myosin II- dependent manner. Interaction with CTNNB1 is necessary for its localization to the cell-cell junctions (By similarity). Colocalizes with LIMD1 in the focal adhesions.
Short Description	Boster Bio Anti-Vinculin VCL Antibody (Catalog# A30448). Tested in WB, IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-Vinculin VCL Antibody (Catalog# A30448). Tested in WB, IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Metavinculin is muscle-specific.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-A30448-datasheet.pdf

BOS-A30448-safety-datasheet.pdf