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Anti-RHG07 DLC1 Antibody

Anti-RHG07 DLC1 Antibody

ArtNr	BOS-A30552
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry Immunofluorescence Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	IF, ICC, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DLC1;ARHGAP7;KIAA1723;STARD12;Rho GTPase-activating protein 7;Deleted in liver cancer 1 protein;DLC-1;HP protein;Rho-type GTPase-activating protein 7;START domain-containing protein 12;StARD12;StAR-related lipid transfer protein
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Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	170591 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry, 1:100 - 1:300 Immunofluorescence, 1:200 - 1:1000 ELISA, 1:10000 Not yet tested in other applications.
Manufacturer - Gene Name	DLC1
Gene Full Name	Rho GTPase-activating protein 7
Immunogen	A peptide derived from human RHG07. Immunogen sequence location: 61-110
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cancer, Cancer Susceptibility, Cell Type Markers, Epigenetics and Nuclear Signaling, G Protein Signaling, Oncoproteins/Suppressors, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins, Tags & Cell Markers, Transcription, Tumor Associated, Tumor Suppressors
Protein Function	Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
Subcellular Localization	Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein. Colocalizes with EF1A1 at actin-rich regions in the cell periphery.
Short Description	Boster Bio Anti-RHG07 DLC1 Antibody (Catalog# A30552). Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-RHG07 DLC1 Antibody (Catalog# A30552). Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Highest level of expression in the spleen, with rather lower levels in prostate, testis, ovary, small intestine and colon, but none in the thymus.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A30552-datasheet.pdf

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