Anti-MARCH2 MARCH2; Antibody

ArtNr	BOS-A30660
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Immunofluorescence Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	IF, ICC, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MARCH2;RNF172;HSPC240;E3 ubiquitin-protein ligase MARCH2;Membrane-associated RING finger protein 2;Membrane-associated RING-CH protein II;MARCH-II;RING finger protein 172
Lieferbar
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	26995 MW
Clonality	Polyclonal
Application Details	Immunohistochemistry, 1:100 - 1:300 Immunofluorescence, 1:200 - 1:1000 ELISA, 1:40000 Not yet tested in other applications.
Manufacturer - Gene Name	MARCH2;
Gene Full Name	E3 ubiquitin-protein ligase MARCH2
Immunogen	A peptide derived from human MARCH2. Immunogen sequence location: 191-240
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Protein Function	E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6.
Subcellular Localization	Endoplasmic reticulum membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Short Description	Boster Bio Anti-MARCH2 MARCH2; Antibody (Catalog# A30660). Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.
Description	Boster Bio Anti-MARCH2 MARCH2; Antibody (Catalog# A30660). Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.
Tissue Specificity	Broadly expressed.

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BOS-A30660-datasheet.pdf

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