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Anti-MEK2 C-Term MAP2K2 Monoclonal Antibody Biotin Europäischer Partner

ArtNr BOS-B00996
Hersteller Boster
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Lyophilized
Applikationen WB
Clon 12A6.G1.G11 IgG1 kappa
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag Biotin
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias MEK2 biotin conjugation, MEK2, MAP2K2, MEK, MEK 2, MKK2, PRKMK2, CFC4, MEK-2
Lieferbar
Manufacturer - Category
Primary Antibodies, Monoclonal Antibodies
Storage Conditions
Store vial at 4°C prior to restoration. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Observed Molecular Weight
44424 MW
Clonality
Monoclonal
Application Details
Anti-MEK 2 Biotin Conjugated (MOUSE) Antibody is suitable for use in Western Blotting and ELISA. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 44 kDa.
Manufacturer - Gene Name
MAP2K2
Gene Full Name
Fibronectin
Background
MEK2 antibodies detect the MEK2 isoform. Mitogen-activated protein kinase kinase 2, also known as MEK2 or MKK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 2 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. MEK1 and MEK2 are about 80% identical to each other, and nearly identical within the kinase domain. This antibody does not react with MEK1. The MEK2 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.
Immunogen
Anti-MEK2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the C-terminus conjugated to KLH.
Contents
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free, 0.01% (w/v) Sodium Azide
Purification
This biotin conjugated protein A purified mouse monoclonal antibody reacts specifically with human MEK2. Anti-MEK2 is purified from tissue culture supernatant by protein A purification. Cross-reactivity is expected to occur with human, mouse, and rat based on sequence identity of the peptide immunogen. This antibody does not react with the MEK1 isoform.
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Concentration
1.0 mg/mL by UV absorbance at 280 nm
Protein Function
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
Short Description
Boster Bio Anti-MEK2 C-Term MAP2K2 Monoclonal Antibody Biotin (Catalog # B00996). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Description
Boster Bio Anti-MEK2 C-Term MAP2K2 Monoclonal Antibody Biotin (Catalog # B00996). Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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