Anti-HDAC2 Antibody (Monoclonal)

At -20°C for one year, at 4°C for one month. Avoid repeated freezing and thawing.

Monoclonal

HDAC2 belongs to the family of histone deacetylases which catalyse the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Acetylation and deacetylation of these highly conserved lysine residues is important for the control of gene expression and HDAC2 activity is associated with gene repression. Histone deacetylation is established by the formation of large multiprotein complexes. Thereby, HDAC2 associates with many different proteins, including the mammalian zinc-finger transcription factor YY1. HDAC2 thus plays an important role in transcriptional regulation, cell cycle progression and developmental events.

Protein A purified monoclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.

The concentration of the antibody is 2.0 ug/ul

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.