Anti-Methyl-CpG-binding protein 2 MeCP2 Antibody

Store at -20°C. For long-term storage, store at -80°C. Avoid multiple freeze-thaw cycles.

Polyclonal

MECP2

MeCP2 is a chromosomal protein with abundant binding sites in the chromatin. It belongs to the family of methyl CpG binding proteins which also comprises MBD1, MBD2, MBD3 and MBD4. MeCP2 can bind specifically to methylated promoters, thereby repressing transcription. This transcriptional repression is mediated through interaction with histone deacetylase and the corepressor SIN3A. MeCP2 also is essential for development. Mutations in MeCP2 are the cause of several types of mental retardation including Rett syndrome, a progressive neurological disorder that causes mental retardation in females and mental retardation syndromic X-linked type 13, and may also be involved in Angelman syndrome and susceptibility to some types of autism.

Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.

0.5-1 mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Methyl-CpG-binding protein 2

Boster Bio Anti-Methyl-CpG-binding protein 2 MeCP2 Antibody (Catalog# CI1047). Tested in ChIP, ELISA, WB applications. This antibody reacts with Human.

Present in all adult somatic tissues tested.