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Anti-POMC Monoclonal Antibody Europäischer Partner

ArtNr BOS-M00305-1
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, IP, IHC
Clon ADEC-16
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Vasodilator-stimulated phosphoprotein;VASP;VASP;
Lieferbar
Manufacturer - Category
Rabbit Monoclonal Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
62 kDa
Calculated Molecular weight
39830 MW
Clonality
Monoclonal
Application Details
WB 1:500-1:2000
IHC 1:100-1:500
IP 1:50
Manufacturer - Gene Name
POMC
Gene Full Name
Vasodilator-stimulated phosphoprotein
Immunogen
A synthesized peptide derived from human POMC ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Cancer, Cancer Metabolism, Endocrine Metabolism, Endocrine System, Energy Metabolism, Growth Factors/Hormones, Hormone Biosynthesis, Metabolic Signaling Pathway, Metabolism, Neurology Process, Neuropeptides, Neuroscience, Neurotransmitter, Pathways and Processes, Signal Transduction, Tumor Biomarkers
Protein Name
P2X purinoceptor 1
Protein Function
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin- bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
Subcellular Localization
Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell junction, tight junction. Cell projection, lamellipodium membrane. Cell projection, filopodium membrane. Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members. Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions. Localized along the sides of actin filaments throughout the peripheral cytoplasm under basal conditions. In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes).
Description
Boster Bio Anti-POMC Monoclonal Antibody catalog # M00305-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Highly expressed in platelets.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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