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Anti-CD45 PTPRC Rabbit Monoclonal Antibody, Clone#RM291

Anti-CD45 PTPRC Rabbit Monoclonal Antibody, Clone#RM291

ArtNr	BOS-M00555-2
Hersteller	Boster
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Carcinoma Hematology Leukemia Immunohistochemistry Western Blot Primary Antibodies Progenitor Markers
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IHC
Clon	RM291
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Receptor-type tyrosine-protein phosphatase C;3.1.3.48;Leukocyte common antigen;L-CA;T200;CD45;PTPRC;CD45;
Lieferbar
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, Rabbit Monoclonal Antibodies, 2279
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	147254 MW
Clonality	Monoclonal
Application Details	Immunohistochemistry (IHC): 1:100-1:200 dilution WB: 1:1000-1:2000 dilution.
Manufacturer - Gene Name	PTPRC
Gene Full Name	Receptor-type tyrosine-protein phosphatase C
Immunogen	A peptide corresponding to the C-terminus of human CD45 (Receptor-type tyrosine-protein phosphatase C).
Contents	50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification	Protein A affinity purified from an animal origin-free culture supernatant
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Adapters, Adaptive Immunity, B Cells, Cell Type Markers, Immunology, Protein Phosphorylation, Signal Transduction, T Cells, Transmembrane, Tyrosine Phosphatases
Protein Function	Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Subcellular Localization	Membrane; Single-pass type I membrane protein. Membrane raft. Colocalized with DPP4 in membrane rafts.
Short Description	Boster Bio Anti-CD45 PTPRC Rabbit Monoclonal Antibody, Clone#RM291 (Catalog # M00555-2). Tested in IHC, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-CD45 PTPRC Rabbit Monoclonal Antibody, Clone#RM291 (Catalog # M00555-2). Tested in IHC, WB applications. This antibody reacts with Human.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-M00555-2-datasheet.pdf

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