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Anti-MMP14/Mt1 Mmp Rabbit Monoclonal Antibody

Anti-MMP14/Mt1 Mmp Rabbit Monoclonal Antibody

ArtNr	BOS-M00656
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, IP, IHC, ICC
Clon	BFD-13
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Matrix metalloproteinase-14;MMP-14;3.4.24.80;MMP-X1;Membrane-type matrix metalloproteinase 1;MT-MMP 1;MTMMP1;Membrane-type-1 matrix metalloproteinase;MT1-MMP;MT1MMP;MMP14;
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Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	44 kDa
Calculated Molecular weight	65894 MW
Clonality	Monoclonal
Application Details	WB 1:1000-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50 FC 1:50
Manufacturer - Gene Name	MMP14
Gene Full Name	Matrix metalloproteinase-14
Immunogen	A synthesized peptide derived from human MMP14
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Metabolism, Metabolism Processes, Metalloprotease, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes, Response To Hypoxia, Signal Transduction, Tumor Biomarkers
Protein Name	T-cell surface glycoprotein CD4
Protein Function	Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro- MMP2.
Subcellular Localization	Membrane; Single-pass type I membrane protein. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Forms a complex with BST2 and localizes to the cytoplasm.
Description	Boster Bio Anti-MMP14/Mt1 Mmp Rabbit Monoclonal Antibody catalog # M00656. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in stromal cells of colon, breast, and head and neck. Expressed in lung tumors.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00656-datasheet.pdf

BOS-M00656-safety-datasheet.pdf