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Anti-SHP1 PTPN6 Rabbit Monoclonal Antibody

Anti-SHP1 PTPN6 Rabbit Monoclonal Antibody

ArtNr	BOS-M00938
Hersteller	Boster
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC
Clon	CGH-16
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tyrosine-protein phosphatase non-receptor type 6;3.1.3.48;Hematopoietic cell protein-tyrosine phosphatase;Protein-tyrosine phosphatase 1C;PTP-1C;Protein-tyrosine phosphatase SHP-1;SH-PTP1;PTPN6;HCP, PTP1C;
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Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	78 kDa
Calculated Molecular weight	67561 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200
Manufacturer - Gene Name	PTPN6
Gene Full Name	Tyrosine-protein phosphatase non-receptor type 6
Immunogen	A synthesized peptide derived from human SHP1
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cancer, Cell Biology, Cell Cycle, Developmental Biology, G Protein Signaling, Kinases/Phosphatases, Organogenesis, Signal Transduction, Signaling Pathway
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
Subcellular Localization	Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1.
Description	Boster Bio Anti-SHP1 PTPN6 Rabbit Monoclonal Antibody catalog # M00938. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00938-datasheet.pdf

BOS-M00938-safety-datasheet.pdf