Anti-M6PR IGF2R Rabbit Monoclonal Antibody

ArtNr	BOS-M00951
Hersteller	Boster
Menge	100 ul
Quantity options	100 ul 30 ul
Kategorie	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies By Cell Type Carcinoma Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, IP, IHC, ICC
Clon	DIC-9
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10 pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Cation-independent mannose-6-phosphate receptor,CI Man-6-P receptor,CI-MPR,M6PR,300 kDa mannose 6-phosphate receptor,MPR 300,Insulin-like growth factor 2 receptor,Insulin-like growth factor II receptor,IGF-II receptor,M6P/IGF2 receptor,M6P/IGF2R,CD222,IGF2R,MPRI
Lieferbar
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	28 kDa
Calculated Molecular weight	274375 MW
Clonality	Monoclonal
Application Details	WB 1:1000-5000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:30 FC 1:100
Gene Name	IGF2R
Gene Full Name	Cation-independent mannose-6-phosphate receptor
Immunogen	A synthesized peptide derived from human M6PR
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	Signal Transduction, Subcellular Markers
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Subcellular Localization	Lysosome membrane; Single-pass type I membrane protein. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface.
Description	Boster Bio Anti-M6PR IGF2R Rabbit Monoclonal Antibody catalog # M00951. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in the excretory system, thyroid gland and Wilms tumors.
Manufacturer - Alias	Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R, CD222, IGF2R, MPRI

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BOS-M00951-datasheet.pdf

BOS-M00951-safety-datasheet.pdf