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Anti-NFAT1 NFATC2 Rabbit Monoclonal Antibody

Anti-NFAT1 NFATC2 Rabbit Monoclonal Antibody

ArtNr	BOS-M00969
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Targets for Rodent Neurosciences Antibodies Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB
Clon	AAFG-14
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Nuclear factor of activated T-cells, cytoplasmic 2;NF-ATc2;NFATc2;NFAT pre-existing subunit;NF-ATp;T-cell transcription factor NFAT1;NFATC2;NFAT1, NFATP;
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Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	150 kDa
Calculated Molecular weight	100146 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000
Manufacturer - Gene Name	NFATC2
Gene Full Name	Nuclear factor of activated T-cells, cytoplasmic 2
Immunogen	A synthesized peptide derived from human NFAT1
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Adaptive Immunity, Cytokines, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Nuclear Signaling, Nuclear Signaling Pathways, Signal Transduction, Signaling Pathway
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.
Subcellular Localization	Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.
Description	Boster Bio Anti-NFAT1 NFATC2 Rabbit Monoclonal Antibody catalog # M00969. Tested in WB application. This antibody reacts with Human.
Tissue Specificity	Expressed in thymus, spleen, heart, testis, brain, placenta, muscle and pancreas. Isoform 1 is highly expressed in the small intestine, heart, testis, prostate, thymus, placenta and thyroid. Isoform 3 is highly expressed in stomach, uterus, placenta, trachea and thyroid.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00969-datasheet.pdf

BOS-M00969-safety-datasheet.pdf