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Anti-Ubiquitin C-terminal Hydrolase 1 (UCHL1) Monoclonal Antibody

Anti-Ubiquitin C-terminal Hydrolase 1 (UCHL1) Monoclonal Antibody

ArtNr	BOS-M01018-3
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Antibodies Cell Biology Cell Status Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Autophagy Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB, IF, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Horse (Equine), Pig (Porcine, Sus scrofa domesticus), Cattle (Bovine)
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ubiquitin carboxyl-terminal hydrolase isozyme L1;UCH-L1;3.4.19.12;6.-.-.-;Neuron cytoplasmic protein 9.5;PGP 9.5;PGP9.5;Ubiquitin thioesterase L1;UCHL1;
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Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, 2279
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	24824 MW
Clonality	Monoclonal
Application Details	Western blot: 1:20, 000. ICC/IF and IHC: 1:2, 000.
Manufacturer - Gene Name	UCHL1
Gene Full Name	Ubiquitin carboxyl-terminal hydrolase isozyme L1
Immunogen	Recombinant full length human UCHL1 purified from E. coli.
Contents	Purified antibody at 1mg/mL in 50% PBS, 50% glycerol plus 5mM NaN₃
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Protein Function	Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Subcellular Localization	Cytoplasm. Endoplasmic reticulum membrane; Lipid-anchor. About 30% of total UCHL1 is associated with membranes in brain.
Short Description	Boster Bio Anti-Ubiquitin C-terminal Hydrolase 1 (UCHL1) Monoclonal Antibody catalog # M01018-3. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Bovine, Equine, Human, Mouse, Pig, Rat.
Description	Boster Bio Anti-Ubiquitin C-terminal Hydrolase 1 (UCHL1) Monoclonal Antibody catalog # M01018-3. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Bovine, Equine, Human, Mouse, Pig, Rat.
Tissue Specificity	Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-M01018-3-datasheet.pdf

BOS-M01018-3-safety-datasheet.pdf