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Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody

Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody

Hersteller	Boster
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Antibodies By Cell Type Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Immunohistochemistry Immunofluorescence Primary Antibodies
Typ	Antibody Monoclonal
Specific against	Human
Clon	LPFS2/1611
Isotype	IgG1 Kappa
Format	Liquid
Applikationen	FC, IF, IHC, ELISA
Menge	100ug
Host	Mouse
ArtNr	BOS-M01148
Targets	TNF
eClass 6.1	32160702
eClass 9.0	42030590
Lieferbar
Manufacturers Product Category	Primary Antibodies, Monoclonal Antibodies
Manufacturers Research Category	Adaptive Immunity, Cancer, Cytokines, Hematopoietic Progenitors, Immunology, Innate Immunity, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage, TNF Superfamily, Tumor Immunology
Short Description	Boster Bio Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody (Catalog # M01148). Tested in ELISA, Flow Cytometry, IF, IHC applications. This antibody reacts with Human.
Description	Boster Bio Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody (Catalog # M01148). Tested in ELISA, Flow Cytometry, IF, IHC applications. This antibody reacts with Human.
Background	Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.
Gene Name	CD27
Clonality	Monoclonal
Concentration	Purified antibody with BSA and azide at 200ug/ml
Contents	Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Application Details	ELISA (For coating, order antibody without BSA) Flow Cytometry (1-2ug/million cells) Immunofluorescence (1-2ug/ml) Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
Immunogen	Recombinant full-length human CD27 protein
Purification	200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Gene Full Name	CD27 antigen
Molecular Weight	29137 MW
Protein Function	Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Subcellular Localization	Cell Surface
Tissue Specificity	Found in most T-lymphocytes.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100ug

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Lieferung vsl. bis 16.05.2024

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