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Anti-Neuropilin 1 NRP1 Rabbit Monoclonal Antibody

Anti-Neuropilin 1 NRP1 Rabbit Monoclonal Antibody

ArtNr	BOS-M01324
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, IP, IHC, ICC
Clon	BGO-14
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Neuropilin-1;Vascular endothelial cell growth factor 165 receptor;CD304;NRP1;NRP, VEGF165R;
Lieferbar
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	38-42 kDa
Calculated Molecular weight	103134 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50 FC 1:50
Manufacturer - Gene Name	NRP1
Gene Full Name	Neuropilin-1
Immunogen	A synthesized peptide derived from human Neuropilin 1
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Adaptive Immunity, Angiogenesis, Axonal Guidance Proteins, Cardiovascular, Growth and Development, Growth Factors, Immunology, Neurology Process, Neuroscience
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.
Subcellular Localization	Cell membrane; Single-pass type I membrane protein.
Description	Boster Bio Anti-Neuropilin 1 NRP1 Rabbit Monoclonal Antibody catalog # M01324. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	The expression of isoforms 1 and 2 does not seem to overlap. Isoform 1 is expressed by the blood vessels of different tissues. In the developing embryo it is found predominantly in the nervous system. In adult tissues, it is highly expressed in heart and placenta; moderately in lung, liver, skeletal muscle, kidney and pancreas; and low in adult brain. Isoform 2 is found in liver hepatocytes, kidney distal and proximal tubules.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M01324-datasheet.pdf

BOS-M01324-safety-datasheet.pdf