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Anti-IDE/Insulysin Rabbit Monoclonal Antibody

Anti-IDE/Insulysin Rabbit Monoclonal Antibody

ArtNr	BOS-M01358
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC
Clon	AOOB-9
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Insulin-degrading enzyme;3.4.24.56;Abeta-degrading protease;Insulin protease;Insulinase;Insulysin;IDE;
Lieferbar
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	118 kDa
Calculated Molecular weight	117968 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:100
Manufacturer - Gene Name	IDE
Gene Full Name	Insulin-degrading enzyme
Immunogen	A synthesized peptide derived from human IDE
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Alzheimer's Disease, Atherosclerosis, Cancer, Cardiovascular, Cell Biology, Diabetes, Diabetes-associated, Growth Factors/Hormones, Heart Disease, Metabolism, Metalloprotease, Neurodegenerative Disease, Neurology Process, Neuroscience, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia.
Subcellular Localization	Cytoplasm. Cell membrane. Secreted. Present at the cell surface of neuron cells. The membrane-associated isoform is approximately 5 kDa larger than the known cytosolic isoform.
Description	Boster Bio Anti-IDE/Insulysin Rabbit Monoclonal Antibody catalog # M01358. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in endoderm, intestinal epithelial cells and in most extraembryonic tissues.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M01358-datasheet.pdf

BOS-M01358-safety-datasheet.pdf