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Anti-GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Monoclonal Antibody

Anti-GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Monoclonal Antibody

ArtNr	BOS-M02393
Hersteller	Boster
Menge	100 ug
Kategorie	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Carcinoma Sarcoma Immunohistochemistry Immunofluorescence Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, FC, IF, IHC
Clon	SPM249
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian), Rabbit (Oryctolagus cuniculus), Guinea Pig, Sheep (Ovine, Ovis aries), Hamster, Chicken (Gallus gallus domesticus), Dog (Canine, Canis lupus familiaris), Horse (Equine), Pig (Porcine, Sus scrofa domesticus), Cow (Bos taurus), Xenopus laevis
Host	Rat
Isotype	IgG2a Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Endoplasmin;94 kDa glucose-regulated protein;GRP-94;Heat shock protein 90 kDa beta member 1;Tumor rejection antigen 1;gp96 homolog;HSP90B1;GRP94, TRA1;
Lieferbar
Specificity	Human,Monkey,Horse,Cow,Sheep,Pig,Rabbit,Dog,Rat,Mouse,Hamster,Guinea pig,Chicken,Xenopus laevis
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, 2279
Storage Conditions	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Observed Molecular Weight	92469 MW
Clonality	Monoclonal
Application Details	Flow Cytometry (1-2ug/million cells) Immunofluorescence (1-2ug/ml) Western Blot (1-2ug/ml) Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
Manufacturer - Gene Name	HSP90B1
Gene Full Name	Endoplasmin
Background	Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This monoclonal antibody is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp' s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
Immunogen	Purified glucose regulated protein 94 (grp94) from chicken oviducts
Contents	Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Purification	200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Concentration	Purified antibody with BSA and azide at 200ug/ml
Manufacturer - Research Category	Cancer, Cancer Metabolism, ER Proteins, Metabolism, Metabolism Processes, Organelles, Pathways and Processes, Protein Trafficking, Response To Hypoxia, Signal Transduction, Subcellular Markers, Tags & Cell Markers
Protein Function	Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.
Subcellular Localization	Cytoplasmic and Nuclear
Short Description	Boster Bio Anti-GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Monoclonal Antibody (Catalog # M02393). Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Monkey, Horse, Cow, Sheep, Pig, Rabbit, Dog, Rat, Mouse, Hamster, Guinea pig, Chicken, Xenopus laevis.
Description	Boster Bio Anti-GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Monoclonal Antibody (Catalog # M02393). Tested in Flow Cytometry, IF, WB, IHC applications. This antibody reacts with Human, Monkey, Horse, Cow, Sheep, Pig, Rabbit, Dog, Rat, Mouse, Hamster, Guinea pig, Chicken, Xenopus laevis.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-M02393-datasheet.pdf

BOS-M02393-safety-datasheet.pdf