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Anti- Alpha-internexin/NF66 Monoclonal Antibody

Anti- Alpha-internexin/NF66 Monoclonal Antibody

ArtNr	BOS-M03756-1
Hersteller	Boster
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Targets for Rodent Neurosciences Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Primary Antibodies Oligodendrocyte Markers
Typ	Antibody Monoclonal
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Cattle (Bovine)
Host	Mouse
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Integrin alpha ina-1;ina-1;F54G8.3;
Lieferbar
Manufacturer - Category	Primary Antibodies, Monoclonal Antibodies, 2279
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	127767 MW
Clonality	Monoclonal
Application Details	WB: 1:10, 000. IF/ICC and IHC: 1:5, 000.
Manufacturer - Gene Name	ina-1
Gene Full Name	Integrin alpha ina-1
Immunogen	Purified recombinant rat -internexin expressed in and purified from E. coli.
Contents	Purified at 1mg/mL in PBS, 50% glycerol, 5mM NaN3
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Protein Function	Plays a role in cell migration, axon fasciculation, and morphogenesis (PubMed:9247263). During gonad morphogenesis, involved in distal tip cells (DTC)-mediated guidance of gonad elongation, in maintaining their sharp tapering morphology and in their migration (PubMed:19023419, PubMed:22732572). Involved in the anterior-posterior positioning of QR neuroblast descendants by regulating the migratory speed of QR.p (PubMed:25373777). Probably by acting as a receptor for apoptotic cells, plays a role in the clearance of apoptotic cells during mid-embryogenesis (PubMed:20226672).
Subcellular Localization	Membrane; Single-pass type I membrane protein. Cell projection, phagocytic cup. Cytoplasmic vesicle, phagosome membrane. Enriched at the cell contact with apoptotic cells and in phagocytic pseudopods during apoptotic cell engulfment. Co-localizes with src-1 during phagosome cup formation.
Short Description	Boster Bio Anti- Alpha-internexin/NF66 Monoclonal Antibody catalog # M03756-1. Tested in IF, IHC, WB applications. This antibody reacts with Bovine, Human, Mouse, Rat.
Description	Boster Bio Anti- Alpha-internexin/NF66 Monoclonal Antibody catalog # M03756-1. Tested in IF, IHC, WB applications. This antibody reacts with Bovine, Human, Mouse, Rat.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-M03756-1-datasheet.pdf

BOS-M03756-1-safety-datasheet.pdf