Hersteller |
Boster
|
Kategorie |
|
Typ |
Antibody Primary |
Specific against |
Human |
Clon |
RM161 |
Isotype |
IgG |
Format |
Liquid |
Applikationen |
WB, IHC, ICC, ELISA, CHIP |
Menge |
100ug |
Host |
Rabbit |
ArtNr |
BOS-M06819-11 |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies, Monoclonal Antibodies |
Manufacturers Research Category |
Epigenetics and Nuclear Signaling, Histones |
Short Description |
Boster Bio Anti-Acetyl-Histone H3 (Lys9) H3F3A Rabbit Monoclonal Antibody, Clone#RM161 (Catalog # M06819-11). Tested in WB, ICC, ChIP, IHC, ELISA, Luminex applications. This antibody reacts with Human, Vertebrates. |
Description |
Boster Bio Anti-Acetyl-Histone H3 (Lys9) H3F3A Rabbit Monoclonal Antibody, Clone#RM161 (Catalog # M06819-11). Tested in WB, ICC, ChIP, IHC, ELISA, Luminex applications. This antibody reacts with Human, Vertebrates. |
Gene Name |
H3F3A |
Clonality |
Monoclonal |
Concentration |
1 mg/mL |
Contents |
50% Glycerol/PBS with 1% BSA and 0.09% sodium azide |
Application Details |
WB: 0.25 ug/mL - 1 ug/mL
ICC: 0.5 ug/mL - 2 ug/mL
ChIP: 2 ug/mL-10 ug/mL
IHC: 0.1 ug/mL – 1 ug/mL
ELISA: 0.2 ug/mL - 1 ug/mL
Luminex: 0.05 ug/mL – 0.5 ug/mL. |
Immunogen |
An acetyl-peptide corresponding to the Acetyl-Histone H3 (Lys9) |
Cross-reactivity |
This antibody reacts to Histone H3 acetylated at Lysine 9 (K9ac). No cross-reactivity with other acetylated Lysines in histone H3. |
Purification |
Protein A affinity purified from an animal origin-free culture supernatant |
Storage |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Histone H3.3 |
Molecular Weight |
15328 MW |
Protein Function |
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Localization |
Nucleus. Chromosome. |
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