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Anti-Phospho-MLK3 (Ser674) MAP3K11 Antibody

Anti-Phospho-MLK3 (Ser674) MAP3K11 Antibody

ArtNr	BOS-P04412
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Signaling Antibodies Western Blot Primary Antibodies Glial Cell Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Mitogen-activated protein kinase kinase kinase 11;2.7.11.25;Mixed lineage kinase 3;Src-homology 3 domain-containing proline-rich kinase;MAP3K11 ;MLK3 , PTK1, SPRK ;
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	92688 MW
Clonality	Polyclonal
Application Details	Western blotting: 1/500 - 1/2000 ELISA: 1/5000 Not yet tested in other applications.
Manufacturer - Gene Name	MAP3K11
Gene Full Name	Mitogen-activated protein kinase kinase kinase 11
Immunogen	Synthesized peptide derived from human MLK3 around the phosphorylation site of S674.
Contents	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Tyrosine Kinases
Protein Function	Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
Subcellular Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Location is cell cycle dependent.
Short Description	Boster Bio Anti-Phospho-MLK3 (Ser674) MAP3K11 Antibody (Catalog # P04412). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-Phospho-MLK3 (Ser674) MAP3K11 Antibody (Catalog # P04412). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in a wide variety of normal and neoplastic tissues including fetal lung, liver, heart and kidney, and adult lung, liver, heart, kidney, placenta, skeletal muscle, pancreas and brain.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-P04412-datasheet.pdf

BOS-P04412-safety-datasheet.pdf