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Anti-Beta-nerve growth factor NGF Antibody Picoband®

Anti-Beta-nerve growth factor NGF Antibody Picoband®

ArtNr	BOS-PA1056
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Western Blot Primary Antibodies By Organ Colorectal Cancer
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<1pg/ml
Citations	1. Dracopoli, N. C.; Rose, E.; Whitfield, G. K.; Guidon, P. T.; Bale, S. J.; Chance, P. A.; Kourides, I. A.; Housman, D. E. : Two thyroid hormone regulated genes, the beta-subunits of nerve growth factor (NGFB) and thyroid stimulating hormone (TSHB), are located less than 310 kb apart in both human and mouse genomes. Genomics 3: 161-167, 1988. 2. Francke, U.; de Martinville, B.; Coussens, L.; Ullrich, A. : The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. Science 222: 1248-1251, 1983 3. Einarsdottir, E.; Carlsson, A.; Minde, J.; Toolanen, G.; Svensson, O.; Solders, G.; Holmgren, G.; Holmberg, D.; Holmberg, M. : A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception. Hum. Molec. Genet. 13: 799-805, 2004.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Beta-nerve growth factor;Beta-NGF;NGF;NGFB;
Similar products	Beta nerve growth factor antibody, Beta nerve growth factor precursor antibody, Beta NGF antibody, Beta-nerve growth factor antibody, Beta-NGF antibody, HSAN5 antibody, MGC161426 antibody, MGC161428 antibody, Nerve growth factor beta antibody, Nerve growth factor beta polypeptide antibody, Nerve growth factor beta subunit antibody, NGF antibody, NGF B antibody, NGF_HUMAN antibody, NGFB antibody, NID67 antibody
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Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	60 kDa
Calculated Molecular weight	26959 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5?g/ml, Human, Rat, Mouse
Manufacturer - Gene Name	NGF
Gene Full Name	Beta-nerve growth factor
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Nerve growth factor is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. The nucleotide sequence of human and mouse beta-NGF are very similar. The beta-subunits of nerve growth factor (NGFB) have been assigned to mouse chromosome 3 and human chromosome 1p22. The human gene for the beta subunit of nerve growth factor is located on the proximal short arm of chromosome 1. A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human NGF, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Growth and Development, Mesenchymal Stem Cells, Neural Stem Cells, Neurology Process, Neuroscience, Stem Cells, Surface Molecules
Protein Name	Beta-nerve growth factor(Beta-NGF)
Protein Function	Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
Subcellular Localization	Secreted.
Description	Boster Bio Anti-Beta-nerve growth factor NGF Antibody catalog # PA1056. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Sequence Similarities	Belongs to the NGF-beta family.

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