Anti-Fas Ligand/FASLG Antibody

ArtNr	BOS-PA1101
Hersteller	Boster
Menge	100 ug/vial
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Cardiovascular Research Ischemia & Reperfusion Injury Enzymes Fatty Acid Synthesis Primary Antibodies By Organ Lung Cancer
Typ	Antibody Polyclonal
Format	Lyophilized
Applikationen	WB, IHC, ICC
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	1. Takahashi, T.; Tanaka, M.; Inazawa, J.; Abe, T.; Suda, T.; Nagata, S. : Human Fas ligand: gene structure, chromosomal location and species specificity. Int. Immun. 6: 1567-1574, 1994. 2. Zhang, X.; Miao, X.; Sun, T.; Tan, W.; Qu, S.; Xiong, P.; Zhou, Y.; Lin, D. : Functional polymorphisms in cell death pathway genes FAS and FASL contribute to the risk of lung cancer. J. Med. Genet. 42: 479-484, 2005. 3. Villa-Morales, M.; Santos, J.; Perez-Gomez, E.; Quintanilla, M.; Fernandez-Piqueras, J. : A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas. Cancer Res. 67: 5107-5116, 2007.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALPS1B antibody, APO1L antibody, Apoptosis(APO 1) antigen ligand 1 antibody, Apoptosis antigen ligand 1 antibody, Apoptosis antigen ligand antibody, APT1LG1 antibody, APTL antibody, CD178 antibody, CD178 antigen antibody, CD95 ligand antibody, CD95-L antibody, CD95L antibody, CD95L protein antibody, FAS antigen ligand antibody, Fas L antibody, Fas ligand(TNF superfamily member 6) antibody, Fas ligand antibody, FASL antibody, Fasl Fas ligand(TNF superfamily member 6) antibody, FASLG antibody, Generalized lymphoproliferative disease antibody, Gld antibody, soluble form antibody, TNF superfamily member 6 antibody, TNFL6_HUMAN antibody, TNFSF6 antibody, Tumor necrosis factor(ligand) superfamily member 6 antibody, Tumor necrosis factor ligand superfamily member 6 antibody
Similar products	soluble form antibody, ALPS1B antibody, APO1L antibody, Apoptosis(APO 1) antigen ligand 1 antibody, Apoptosis antigen ligand 1 antibody, Apoptosis antigen ligand antibody, APT1LG1 antibody, APTL antibody, CD178 antibody, CD178 antigen antibody, CD95 ligand antibody, CD95-L antibody, CD95L antibody, CD95L protein antibody, FAS antigen ligand antibody, Fas L antibody, Fas ligand(TNF superfamily member 6) antibody, Fas ligand antibody, FASL antibody, Fasl Fas ligand(TNF superfamily member 6) antibody, FASLG antibody, Generalized lymphoproliferative disease antibody, Gld antibody, TNF superfamily member 6 antibody, TNFL6_HUMAN antibody, TNFSF6 antibody, Tumor necrosis factor(ligand) superfamily member 6 antibody, Tumor necrosis factor ligand superfamily member 6 antibody
Lieferbar
Specificity	No cross reactivity with other proteins.
Storage Conditions	At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time. Avoid repeated freezing and thawing.
Manufacturer - Gene Name	FASLG
Gene Full Name	Vascular endothelial growth factor A
Background	FAS Ligand(FASL) is a 40 kDa type II membrane protein belonging to the tumor necrosis factor family, which induces apoptosis by binding to its receptor, Fas. The human FasL gene consists of approximately 8.0 kb and is split into four exons. This gene consists of 281 amino acids with a calculated M(r) of 31, 759 and was mapped on chromosome 1q23. It has an identity of 76.9% at the amino acid sequence level with mouse FasL. The FAS and FASL system plays a key role in regulating apoptotic cell death and corruption of this signalling pathway has been shown to participate in immune escape and tumorigenesis. FAS and FASL triggered apoptosis pathway plays an important role in human carcinogenesis. This system may also play a role in modulating the genetic susceptibility of mouse strains to develop T-cell lymphoblastic lymphomas.
Immunogen	A synthetic peptide corresponding to a sequence at the C-terminus of human Fas Ligand(192-218aa YSKVYFRGQSCNNLPLSHKVYMRNSKY), different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Protein Name	Tumor necrosis factor ligand superfamily member 6

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