Anti-Cytokeratin 8/KRT8 Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

53704 MW

Western blot, 0.1-0.5?g/ml, Human, Mouse, Rat

Immunohistochemistry (Paraffin-embedded Section), 2-5?g/ml, Human, By Heat

Flow Cytometry(Fixed), 1-3 ?g/1x10⁶ cells, Human

Keratin, type II cytoskeletal 8

Keratin, type II cytoskeletal 8, also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Class I, Cytoskeleton, Cytoskeleton/ECM, Intermediate Filaments, Keratin, Signal Transduction

Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Boster Bio Anti-Cytokeratin 8/KRT8 Antibody catalog # PA1240. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Belongs to the intermediate filament family.