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Anti-CD82 Antibody Europäischer Partner

ArtNr BOS-PA1307
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CD82 antigen,C33 antigen,IA4,Inducible membrane protein R2,Metastasis suppressor Kangai-1,Suppressor of tumorigenicity 6 protein,Tetraspanin-27,Tspan-27,CD82,CD82,KAI1, SAR2, ST6, TSPAN27,
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Storage Conditions
At -20C for one year, at 4C for one month. Avoid repeated freezing and thawing.
Observed Molecular Weight
29626 MW
Manufacturer - Gene Name
CD82
Gene Full Name
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Background
CD82(Cluster of Differentiation 82), also named KAI1, is a human protein encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. The expression of CD82 protein appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma(ESCC). And the CD82 overexpression can suppress tumor invasiveness and metastatic potential by inducing MMP9 inactivation via upregulation of TIMP1.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human CD82(253-267aa CRHVHSEDYSKVPKY), different from the related mouse and rat sequences by two amino acids.
Contents
Each vial contains 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify Carrier Free" or "No BSA" in your order note. "
Manufacturer - Research Category
|immunology|adaptive immunity|t cells|
immunology|cell type markers|nk cells|platelets|
epigenetics and nuclear signaling|transcription|cancer susceptibility|tumor suppressors|
cancer|oncoproteins/suppressors
Protein Name
CD82 antigen
Protein Function
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.
Tissue Specificity
Lymphoid specific.
Sequence Similarities
Belongs to the tetraspanin (TM4SF) family.
Predicted Reactivity
Hamster

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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