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Anti-TGF alpha/TGFA Antibody Picoband® Europäischer Partner

ArtNr BOS-PA1360
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
Citations 1. In vivo induction of massive proliferation, ed migration, and differentiation of neural cells in the adult mammalian brain.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Protransforming growth factor alpha;Transforming growth factor alpha;TGF-alpha;EGF-like TGF;ETGF;TGF type 1;TGFA;
Similar products EGF like TGF antibody, EGF-like TGF antibody, ETGF antibody, TFGA antibody, TGF A antibody, TGF type 1 antibody, TGF-alpha antibody, TGFA antibody, TGFA_HUMAN antibody, Transforming growth factor alpha antibody, Transforming growth factor alpha precursor antibody, Wa1 antibody, Waved 1 antibody
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Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
6 kDa
Calculated Molecular weight
17006 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Human, Mouse, Rat
Manufacturer - Gene Name
TGFA
Gene Full Name
Protransforming growth factor alpha
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
Transforming growth factor alpha (TGF-alpha) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGFalpha stimulates neural cell proliferation in the adult injured brain. TGFalpha was cited in the 2001 NIH Stem Cell report to the U.S. Congress as promising evidence for the ability of adult stem cells to restore function in neurodegenerative disorders.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human TGF alpha, different from the related mouse and rat sequences by one amino acid.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Angiogenesis, Cancer, Cardiovascular, Growth Factors, Growth Factors/Hormones, Invasion/Microenvironment, Signal Transduction
Protein Name
Protransforming growth factor alpha
Protein Function
TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
Subcellular Localization
Transforming growth factor alpha: Secreted, extracellular space.
Description
Boster Bio Anti-TGF alpha/TGFA Antibody catalog # PA1360. Tested in WB applications. This antibody reacts with Human.
Tissue Specificity
Isoform 1, isoform 3 and isoform 4 are expressed in keratinocytes and tumor-derived cell lines.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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