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Anti-Fibroblast growth factor 10 FGF10 Antibody Picoband® Europäischer Partner

ArtNr BOS-PA1454
Hersteller Boster
Menge 100 ug/vial
Kategorie
Typ Antibody Polyclonal
Format Lyophilized
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
Citations 1. Bagai, S., Rubio, E., Cheng, J.-F., Sweet, R., Thomas, R., Fuchs, E., Grady, R., Mitchell, M., Bassuk, J. A.Fibroblast growth factor-10 is a mitogen for urothelial cells.J. Biol. Chem. 277: 23828-23837, 2002.
2. Emoto, H., Tagashira, S., Mattei, M.-G., Yamasaki, M., Hashimoto, G., Katsumata, T., Negoro, T., Nakatsuka, M., Birnbaum, D., Coulier, F., Itoh, N.Structure and expression of human fibroblast growth factor-10.J. Biol. Chem. 272: 23191-23194, 1997.
3. Umemori, H., Linhoff, M. W., Ornitz, D. M., Sanes, J. R.FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain.Cell 118: 257-270, 2004.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Fibroblast growth factor 10;FGF-10;Keratinocyte growth factor 2;FGF10;
Similar products BB213776 antibody, fd11d03 antibody, FGF 10 antibody, FGF-10 antibody, FGF10 antibody, FGF10_HUMAN antibody, Fibroblast growth factor 10 antibody, Keratinocyte growth factor 2 antibody, KGF 2 antibody, wu:fd11d03 antibody, zgc:109774 antibody
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Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
23 kDa
Calculated Molecular weight
23436 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Human, Rat, Mouse
Manufacturer - Gene Name
FGF10
Gene Full Name
Fibroblast growth factor 10
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
FGF 10, Fibroblast growth factor 10, is a protein that in humans is encoded by the FGF10 gene.The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF 10 contains 3 exons and spans at least 52.7 kb. By radioactive in situ hybridization, the FGF 10 gene is mapped to 5p13-p12. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts. FGF 10 translocated into urothelial cell nuclei and initiated a signaling cascade that began with the heparin-dependent tyrosine phosphorylation of surface transmembrane receptors.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human FGF10, different from the related mouse and rat sequence by two amino acids.
Contents
Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Angiogenesis, Cancer, Cardiovascular, Embryonic Stem Cells, Growth Factors, Growth Factors/Hormones, Secreted, Signal Transduction, Stem Cells
Protein Name
Fibroblast growth factor 10(FGF-10)
Protein Function
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. May play a role in wound healing.
Subcellular Localization
Secreted.
Description
Boster Bio Anti-Fibroblast growth factor 10 FGF10 Antibody catalog # PA1454. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Sequence Similarities
Belongs to the heparin-binding growth factors family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug/vial
Lieferbar: In stock
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