Anti-Kallikrein 1/Ngfg Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

28852 MW

Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Rat, By Heat

Western blot, 0.1-0.5?g/ml, Rat

Kallikrein-1

KLK1 (KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Adaptive Immunity, Host-Virus Interaction, Immune System Diseases, Immunology, Interspecies Interaction, Microbiology, Non-CD, T Cells

May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. May play a role in kidney injury and repair (By similarity).

Boster Bio Anti-Kallikrein 1/Ngfg Antibody catalog # PA1633. Tested in IHC, WB applications. This antibody reacts with Rat.

Belongs to the peptidase S1 family. Kallikrein subfamily.