Filamin A Colorimetric Cell-Based ELISA Kit

Cell-Based ELISA Kits

280739 MW

Filamin-A

Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).

The Filamin A Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Filamin A protein expression profile in cells. The kit can be used for measuring the relative amounts of Filamin A in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Filamin A.

Ubiquitous.