Sodium Channel-pan Colorimetric Cell-Based ELISA Kit

Store at 4°C for up to 6 months.

SCN1A

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na (+) ions may pass in accordance with their electrochemical gradient. Plays a key role in brain, probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neurons induces pain without neurogenic inflammation and produces hypersensitivity to mechanical, but not thermal stimuli.

The Sodium Channel-pan Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Sodium Channel-pan protein expression profile in cells. The kit can be used for measuring the relative amounts of Sodium Channel-pan in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Sodium Channel-pan.