« Zurück
Startseite /
SREBP-1 Colorimetric Cell-Based ELISA Kit

SREBP-1 Colorimetric Cell-Based ELISA Kit

ArtNr	BOS-EKC1538
Hersteller	Boster
Menge	1 kit, containing one 96-well plate and all necessary reagents
Kategorie	Oncology Neuroscience Aging & Neurological Disorders By Cell Type Hematology Myeloma ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Typ	Elisa-Kit
Applikationen	ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Sterol regulatory element-binding protein 1;SREBP-1;Class D basic helix-loop-helix protein 1;bHLHd1;Sterol regulatory element-binding transcription factor 1;Processed sterol regulatory element-binding protein 1;SREBF1;BHLHD1, SREBP1;
Lieferbar
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Observed Molecular Weight	121675 MW
Manufacturer - Gene Name	SREBF1
Gene Full Name	Sterol regulatory element-binding protein 1
Protein Function	Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway (By similarity). Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3').
Subcellular Localization	Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Moves from the endoplasmic reticulum to the Golgi in the absence of sterols.
Short Description	The SREBP-1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SREBP-1 protein expression profile in cells. The kit can be used for measuring the relative amounts of SREBP-1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SREBP-1.
Description	The SREBP-1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SREBP-1 protein expression profile in cells. The kit can be used for measuring the relative amounts of SREBP-1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SREBP-1.
Tissue Specificity	Expressed in a wide variety of tissues, most abundant in liver and adrenal gland. In fetal tissues lung and liver shows highest expression. Isoform SREBP-1C predominates in liver, adrenal gland and ovary, whereas isoform SREBP-1A predominates in hepatoma cell lines. Isoform SREBP-1A and isoform SREBP-1C are found in kidney, brain, white fat, and muscle.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-EKC1538-datasheet.pdf

BOS-EKC1538-safety-datasheet.pdf