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TRADD Colorimetric Cell-Based ELISA Kit Europäischer Partner

ArtNr BOS-EKC1574
Hersteller Boster
Menge 1 kit, containing one 96-well plate and all necessary reagents
Kategorie
Typ Elisa-Kit
Applikationen ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Sensitivity >5000 cells
ECLASS 10.1 32160605
ECLASS 11.0 32160605
UNSPSC 41116126
Alias Tumor necrosis factor receptor type 1-associated DEATH domain protein;TNFR1-associated DEATH domain protein;TNFRSF1A-associated via death domain;TRADD;
Lieferbar
Manufacturer - Category
Cell-Based ELISA Kits
Storage Conditions
Store at 4°C for up to 6 months.
Observed Molecular Weight
34247 MW
Manufacturer - Gene Name
TRADD
Gene Full Name
Tumor necrosis factor receptor type 1-associated DEATH domain protein
Protein Function
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Subcellular Localization
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Shuttles between the cytoplasm and the nucleus.
Short Description
The TRADD Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TRADD protein expression profile in cells. The kit can be used for measuring the relative amounts of TRADD in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TRADD.
Description
The TRADD Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TRADD protein expression profile in cells. The kit can be used for measuring the relative amounts of TRADD in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TRADD.
Tissue Specificity
Found in all examined tissues.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 kit, containing one 96-well plate and all necessary reagents
Lieferbar: In stock
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