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Tuberin/TSC2 Colorimetric Cell-Based ELISA Kit Europäischer Partner

ArtNr BOS-EKC1579
Hersteller Boster
Menge 1 kit, containing one 96-well plate and all necessary reagents
Kategorie
Typ Elisa-Kit
Applikationen ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Sensitivity >5000 cells
ECLASS 10.1 32160605
ECLASS 11.0 32160605
UNSPSC 41116126
Alias Tuberin,Tuberous sclerosis 2 protein,TSC2,TSC4
Lieferbar
Manufacturer - Category
Cell-Based ELISA Kits
Storage Conditions
Store at 4°C for up to 6 months.
Molecular Weight
200608 MW
Gene Name
TSC2
Gene Full Name
Tuberin
Protein Function
In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5.
Subcellular Localization
Cytoplasm. Membrane; Peripheral membrane protein. At steady state found in association with membranes.
Description
The Tuberin/TSC2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Tuberin/TSC2 protein expression profile in cells. The kit can be used for measuring the relative amounts of Tuberin/TSC2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Tuberin/TSC2.
Tissue Specificity
Liver, brain, heart, lymphocytes, fibroblasts, biliary epithelium, pancreas, skeletal muscle, kidney, lung and placenta.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 kit, containing one 96-well plate and all necessary reagents
Lieferbar: In stock
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