KAPCB Colorimetric Cell-Based ELISA

Store at 4°C for up to 6 months.

PRKACB

Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis.

The KAPCB Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor KAPCB protein expression profile in cells. The kit can be used for measuring the relative amounts of KAPCB in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on KAPCB.