NMDAR1 (Phospho-Ser896) Colorimetric Cell-Based ELISA Kit

Cell-Based ELISA Kits

105373 MW

Glutamate receptor ionotropic, NMDA 1

Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg (2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761).

The NMDAR1 (Phospho-Ser896) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor NMDAR1 (Phospho-Ser896) protein expression profile in cells. The kit can be used for measuring the relative amounts of NMDAR1 (Phospho-Ser896) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on NMDAR1 (Phospho-Ser896).