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BCL-XL (Phospho-Ser62) Colorimetric Cell-Based ELISA Kit

BCL-XL (Phospho-Ser62) Colorimetric Cell-Based ELISA Kit

ArtNr	BOS-EKC2364
Hersteller	Boster
Menge	1 kit, containing two 96-well plates and all necessary reagents
Kategorie	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Cell Biology Cell Status Apoptosis ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Typ	Elisa-Kit
Applikationen	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Bcl-2-like protein 1;Bcl2-L-1;Apoptosis regulator Bcl-X;BCL2L1;BCL2L, BCLX;
Lieferbar
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Observed Molecular Weight	26049 MW
Manufacturer - Gene Name	BCL2L1
Gene Full Name	Bcl-2-like protein 1
Protein Function	Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
Subcellular Localization	Isoform Bcl-X (L): Mitochondrion inner membrane. Mitochondrion outer membrane. Mitochondrion matrix. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus membrane; Single-pass membrane protein; Cytoplasmic side. After neuronal stimulation, translocates from cytosol to synaptic vesicle and mitochondrion membrane in a calmodulin-dependent manner (By similarity). Localizes to the centrosome when phosphorylated at Ser-49.
Short Description	The BCL-XL (Phospho-Ser62) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BCL-XL (Phospho-Ser62) protein expression profile in cells. The kit can be used for measuring the relative amounts of BCL-XL (Phospho-Ser62) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on BCL-XL (Phospho-Ser62).
Description	The BCL-XL (Phospho-Ser62) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BCL-XL (Phospho-Ser62) protein expression profile in cells. The kit can be used for measuring the relative amounts of BCL-XL (Phospho-Ser62) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on BCL-XL (Phospho-Ser62).
Tissue Specificity	Bcl-X (S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X (L) is found in tissues containing long-lived postmitotic cells, such as adult brain.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-EKC2364-datasheet.pdf

BOS-EKC2364-safety-datasheet.pdf