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FKHRL1 (Phospho-Ser253) Colorimetric Cell-Based ELISA Kit

FKHRL1 (Phospho-Ser253) Colorimetric Cell-Based ELISA Kit

ArtNr	BOS-EKC2412
Hersteller	Boster
Menge	1 kit, containing two 96-well plates and all necessary reagents
Kategorie	Oncology Neuroscience Targets for Rodent Neurosciences By Cell Type Sarcoma ELISA ELISA & Immunoassays ELISA Kits Immunoassay
Typ	Elisa-Kit
Applikationen	ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Sensitivity	>5000 cells
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Forkhead box protein O3 ;AF6q21 protein ;Forkhead in rhabdomyosarcoma-like 1 ;FOXO3 ;FKHRL1 , FOXO3A ;
Lieferbar
Manufacturer - Category	Cell-Based ELISA Kits
Storage Conditions	Store at 4°C for up to 6 months.
Observed Molecular Weight	71277 MW
Manufacturer - Gene Name	FOXO3 FKHRL1 , FOXO3A
Gene Full Name	Forkhead box protein O3
Protein Function	Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Subcellular Localization	Cytoplasm, cytosol. Nucleus. Retention in the cytoplasm contributes to its inactivation. Translocates to the nucleus upon oxidative stress and in the absence of survival factors.
Short Description	The FKHRL1 (Phospho-Ser253) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor FKHRL1 (Phospho-Ser253) protein expression profile in cells. The kit can be used for measuring the relative amounts of FKHRL1 (Phospho-Ser253) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on FKHRL1 (Phospho-Ser253).
Description	The FKHRL1 (Phospho-Ser253) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor FKHRL1 (Phospho-Ser253) protein expression profile in cells. The kit can be used for measuring the relative amounts of FKHRL1 (Phospho-Ser253) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on FKHRL1 (Phospho-Ser253).
Tissue Specificity	Ubiquitous.

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BOS-EKC2412-datasheet.pdf

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