HDAC8 (Phospho-Ser39) Colorimetric Cell-Based ELISA Kit

Store at 4°C for up to 6 months.

HDAC8

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

The HDAC8 (Phospho-Ser39) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor HDAC8 (Phospho-Ser39) protein expression profile in cells. The kit can be used for measuring the relative amounts of HDAC8 (Phospho-Ser39) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on HDAC8 (Phospho-Ser39).