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MANF Human, Mesencephalic Astrocyte-Derived Neurotrophic Factor Human Recombinant Protein, His Tag

MANF Human, Mesencephalic Astrocyte-Derived Neurotrophic Factor Human Recombinant Protein, His Tag

Hersteller	Boster
Kategorie	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Format	Solution
Menge	20ug
ArtNr	BOS-PROTP55145
Targets	NTF3
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Contents	The MANF solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl, 1mM DTT and 10% glycerol.
Description	MANF Human Recombinant produced in E. coli is a single polypeptide chain containing 183 amino acids (25-182) and having a molecular mass of 20.8kDa. MANF is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Gene name	MANF
Protein function	Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Purification	Greater than 90% as determined by SDS-PAGE.
Shipping	Shipped with wet ice
Short description	MANF Human Recombinant produced in E. Coli is a single polypeptide chain containing 183 amino acids (25-182) and having a molecular mass of 20.8kDa. MANF is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Storage	Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localization	Secreted
Format Information	Sterile Filtered colorless solution.

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Menge: 20ug

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Lieferung vsl. bis 16.05.2024

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