MANF Human, Mesencephalic Astrocyte-Derived Neurotrophic Factor Human Recombinant Protein, His Tag

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Hersteller Boster
Kategorie
Typ Proteins Recombinant
Specific against other
Format Sterile Filtered colorless solution.
Menge 20ug
ArtNr BOS-PROTP55145
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Gene name
MANF
Conjugate
No
Contents
The MANF solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl, 1mM DTT and 10% glycerol.
Description
MANF Human Recombinant produced in E. coli is a single polypeptide chain containing 183 amino acids (25-182) and having a molecular mass of 20.8kDa.
MANF is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Short description
MANF Human Recombinant produced in E. Coli is a single polypeptide chain containing 183 amino acids (25-182) and having a molecular mass of 20.8kDa.
MANF is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Uniprot ID
P55145
Purification
Greater than 90% as determined by SDS-PAGE.
Storage
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Synonyms
Mesencephalic astrocyte-derived neurotrophic factor; Arginine-rich protein; Protein ARMET; MANF; ARMET, ARP;
Protein function
Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Subcellular localization
Secreted
Source
E.coli.
Shipping
Shipped with wet ice

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Menge: 20ug
Lieferbar: In stock
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