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Mouse BAFF Recombinant Protein Europäischer Partner

ArtNr BOS-R01257-3
Hersteller Boster
Menge 5 ug
Kategorie
Typ Proteins
Format Lyophilized
Applikationen Cell Culture
Specific against other
Dry ice Yes
Sequence AFQGPEETEQ DVDLSAPPAP CLPGCRHSQH DDNGMNLRNI IQDCLQLIAD SDTPTIRKGT YTFVPWLLSF KRGNALEEKE NKIVVRQTGY FFIYSQVLYT DPIFAMGHVI QRKKVHVFGD ELSLVTLFRC IQNMPKTLPN NSCYSAGIAR LEEGDEIQLA IPRENAQISR NGDDTFFGAL KLL (183)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Tumor necrosis factor ligand superfamily member 13B; B-cell-activating factor; BAFF; CD257; Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form; Tnfsf13b; Baff
Lieferbar
Manufacturer - Category
Recombinant Proteins
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Manufacturer - Gene Name
TNFSF13B
Contents
Lyophilized without carrier protein.
Purification
Ion-exchange chromatography.
Manufacturer - Research Category
Adaptive Immunity, B Cells, Cancer, Cytokines, Growth Factors, Growth Factors/Hormones, Immunology, Innate Immunity, Non-CD, Signal Transduction, TNF Superfamily
Protein Function
Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
Subcellular Localization
Cell membrane; Single-pass type II membrane protein.
Short Description
BAFF (B-cell Activation Factor), also known as Tumor Necrosis Factor Superfamily member 13B (TNFSF13B), is expressed in B cell lineage cells and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Mouse BAFF Recombinant Protein is purified b-cell activation factor produced in yeast.
Description
BAFF (B-cell Activation Factor), also known as Tumor Necrosis Factor Superfamily member 13B (TNFSF13B), is expressed in B cell lineage cells and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Mouse BAFF Recombinant Protein is purified b-cell activation factor produced in yeast.
Tissue Specificity
Isoform 2 is expressed in many myeloid cell lines.
Bioactivity/Biological Activity
In testing.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5 ug
Lieferbar: In stock
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