CEACAM5 Antibody

ArtNr	PRS-7453-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Quantity options	0.02 mg 0.1 mg
Kategorie	Oncology Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Western Blot ELISA Primary Antibodies By Organ Lung Cancer Gastric Cancer Hepatic Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Gold P and Freedman SO. Specific carinoembryonic antigens of the human digestive system. J. Exp. Med. 1965; 122:467-81. Kuespert K, Pils S, and Hauck CR. CEACAMs: their role in physiology and pathophysiology. Curr. Opin. Cell Biol. 2006; 565-71. Yoshioka T, Masuko T, Kotanagi H, et al. Homotypic adhesion though carcinoembryonic antigen plays a role in hepatic metastasis development. Jpn. J. Cancer Res. 1998; 89:177-85.
NCBI	CEACAM5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CEACAM5 Antibody : CEA, CD66e, CEA, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen
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Manufacturer - Applications	CEACAM5 antibody can be used for detection of CEACAM5 by Western blot at 1 - 2 μg/ml. Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Shipping Temperature	blue ice or room temperature
Storage Conditions	CEACAM5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Molecular Weight	Predicted: 77 kDa Observed: 80kDa
Manufacturer - Research Area	Cancer, Cell Cycle
Background	CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1, 2). CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2). CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3).
Protein Gi #	98986445
Purification	CEACAM5 Antibody is affinity chromatography purified via peptide column.
Positive Control 1	PRS-1462-0.1mg
Positive Control 2	PRS-10-101-4um
Concentration	1 mg/ml
Buffer	CEACAM5 Antibody is supplied in PBS containing 0.02% sodium azide.
Immunogen	CEACAM5 antibody was raised against a 15 amino acid peptide near the center of human CEACAM5. The immunogen is located within amino acids 310 - 360 of CEACAM5 .
Clonality	Polyclonal
NCBI Official Name	carcinoembryonic antigen-related cell adhesion molecule 5
NCBI Organism	homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

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